Author: Paramraj Singh Sondhi

  • Completing the pre-screener

    The pre-screener is the initial step in identifying whether you may qualify for one or more clinical trials listed on the DecenTrialz platform. It is a brief, confidential questionnaire designed to assess general eligibility before any information is shared with research teams.

    This section explains the purpose of the pre-screener, what types of questions you will encounter, and how your information is securely handled.

    Purpose of the pre-screener

    The primary objective of the pre-screener is to gather essential, non-sensitive details about your health background and location. This enables our platform to:

    • Identify clinical trials that align with your general eligibility profile
    • Minimize unnecessary outreach from trials for which you clearly do not qualify
    • Ensure your control over when and how your data is shared with research teams

    Please note: Completing the pre-screener does not enroll you in a clinical trial. It is an optional, informational step intended to help you explore available research opportunities.

    What to expect during the pre-screener

    The pre-screener is divided into two core categories of questions:

    a. Basic health and medical information

    These questions help us determine if you may be a suitable match for clinical trials with specific health-related criteria. You may be asked about:

    • Any current or past medical diagnoses
    • Ongoing medications or therapies
    • Relevant surgical history or major health events
    • Your age and biological sex (required for eligibility in many trials)

    You will not be asked for sensitive data such as your Social Security Number, insurance details, or complete medical records.

    For more information, see below [Health Questions].

    b. Location and contact details

    To ensure you are matched with trials based on geographic feasibility, we will ask for:

    • Your city and state of residence
    • Willingness or ability to travel, if needed
    • Your preferred contact method (e.g., phone number or email address)

    This allows our platform to prioritize studies in your region or those that offer remote participation.

    For more information, see below [Location/Contact Details].

    Estimated completion Time

    The pre-screener typically takes less than five minutes to complete. You may pause the process and return later, provided your browser session remains open.

    Data security and privacy

    Your responses are handled in accordance with the highest data protection standards, including compliance with the Health Insurance Portability and Accountability Act (HIPAA). Specifically:

    • Your information is never shared with any research team without your explicit consent
    • All data is encrypted and stored using secure, access-controlled systems
    • The information you provide is used solely for clinical trial matching and referral — never for commercial advertising or third-party marketing

    Key Note: You are not obligated to complete the pre-screener or proceed beyond any step. You may exit the process at any time. The purpose of the pre-screener is to provide you with a secure, transparent way to explore trial options at your own pace and with full control over your participation decisions.

    Health questions

    As part of the pre-screener process on the DecenTrialz platform, you will be asked a short series of general health questions. These questions are designed to determine whether your current medical profile may preliminarily align with the eligibility criteria of clinical trials listed on our platform.

    This is not a diagnostic evaluation or full medical assessment. Rather, it serves as an early, participant-controlled screening tool to help match you with relevant research opportunities.

    Why these questions are asked

    Each clinical trial is governed by specific inclusion and exclusion criteria that define who may participate. These criteria are determined by the study sponsor or research investigators and often include considerations such as:

    • The medical condition under investigation (e.g., Type 2 Diabetes, Asthma, Anxiety)
    • The severity or stage of the condition
    • Prior diagnoses, treatments, or procedures
    • Current medications, symptoms, or health risks

    The health-related questions in the pre-screener allow the platform to filter out trials that would clearly not be appropriate for your profile. This protects your time, privacy, and avoids unnecessary outreach from research sites.

    Examples of health questions you may encounter

    The following are common categories of questions that may appear in the pre-screener:

    1. Diagnosis or Condition Status

    These questions help assess whether you have previously or currently experience the condition being studied.

    • Have you ever been diagnosed with [specific condition]?
    • Are you currently receiving treatment for this condition?

    2. Treatment History

    These questions identify whether you have undergone relevant medical procedures or used specific medications.

    • Have you taken medication for this condition within the past six months?
    • Have you had any surgeries related to this diagnosis?

    3. Current Symptoms

    These questions gather insight into present-day health experiences that may be relevant to study eligibility.

    • Are you experiencing any of the following symptoms?
    • How often do you experience [specific symptom]?

    4. Other Relevant Medical Factors

    Certain clinical trials require awareness of additional health conditions or physiological states.

    • Are you currently pregnant or breastfeeding?
    • Do you use any implanted medical devices (e.g., pacemaker, insulin pump)?

    Important: You are not required to upload test reports, disclose insurance details, or share physician records at this stage.

    How your responses are used

    • Your responses are automatically compared with the general eligibility filters of active clinical trials.
    • DecenTrialz does not make medical decisions or diagnoses based on your answers.
    • You may review and edit your responses before submitting them.
    • No personal or health-related information is shared with any third party unless you explicitly opt in for referral.

    Key Note: You may skip individual questions or exit the pre-screener entirely at any time. Your participation in the pre-screener is voluntary and confidential. The information you provide is used exclusively to guide your exploration of potential clinical trial opportunities and is never used for advertising or shared for commercial purposes.

    Location and contact details

    In addition to health-related questions, the DecenTrialz pre-screener includes a brief section where you are asked to provide your geographic location and preferred contact method. These details are essential for ensuring that any potential trial matches are geographically relevant or offer remote participation options.

    All information you provide is stored securely and will not be shared with any research team or third party without your explicit consent.

    Why location and contact information are important

    Most clinical trials are hosted at specific research sites, including hospitals, clinics, or academic research institutions. While some studies may offer remote or hybrid options, many still require in-person visits for procedures, labs, or assessments.

    Providing your general location allows DecenTrialz to:

    • Match you with studies near your place of residence or within your preferred travel range
    • Filter out studies that are not available in your region
    • Help identify decentralized or remote-participation trials, when applicable

    Information You May Be Asked to Provide

    The location and contact section of the pre-screener typically requests the following details:

    1. City, state, and country

    You will be asked to enter your current place of residence, which may include:

    • Your city or town
    • The applicable U.S. state (for domestic participants)
    • Your country of residence

    This helps narrow down geographically relevant trials based on eligibility and trial site proximity.

    2. Willingness to travel

    Some studies may ask participants to visit a trial site periodically. You may be asked:

    • Whether you are open to traveling for a clinical study
    • Your maximum preferred travel range (e.g., within 10 miles, 25 miles, or more)

    These questions are optional and do not impact your ability to view or be matched to remote-eligible studies.

    3. Preferred method of contact

    In the event that you are matched to a trial and choose to proceed with a referral, the research team may need a way to contact you. You may be asked for:

    • Your name (optional during pre-screening)
    • A phone number and/or email address
    • Your preferred method of communication (e.g., phone call, text, or email)

    You are free to indicate your contact preferences or opt out of providing this information if you do not wish to proceed further.

    Data privacy and consent

    • Your location and contact details are not shared with any trial site unless you opt in and provide explicit consent
    • If you choose to move forward with a referral, only the information necessary to initiate contact is securely transmitted to the research team
    • You may update or request the deletion of your information at any time by contacting support@decentrialz.com

    Key Note: Providing accurate location and contact information helps improve the precision of trial matching. However, sharing your contact information is entirely voluntary. You will never be contacted by a research site unless you have explicitly agreed to be referred, and you may withdraw or modify your information at any time.

  • How matching works

    DecenTrialz offers a technology-enabled, pre-screening service to help individuals explore potential clinical trials based on preliminary eligibility factors. This process is designed to be secure, efficient, and participant-centered, serving as an entry point to identify research opportunities that may align with your medical profile and location.

    Understanding the trial matching process

    The matching process at DecenTrialz is structured to respect your privacy while providing a simplified path to research participation. It involves the following key steps:

    1. Completion of the pre-screener questionnaire

    Upon expressing interest in clinical trials, you will be guided through a brief questionnaire. This pre-screener collects general information such as:

    • Age and biological sex
    • Relevant medical history or current conditions (if any)
    • Basic geographic details (e.g., ZIP code)

    This step typically takes only a few minutes to complete and does not require access to your full medical records.

    2. Matching your information with study criteria

    Each clinical trial has defined eligibility requirements, also known as inclusion and exclusion criteria. These are determined by the research site or trial sponsor and may include factors such as:

    • Diagnosis or symptom history
    • Medication usage
    • Lifestyle factors or risk exposure

    Your responses are algorithmically and securely compared against these criteria to identify potential trial matches. Sensitive data is handled with strict privacy safeguards and used solely for the purpose of generating preliminary matches.

    3. Viewing potential study matches

    If your responses indicate that you may preliminarily qualify for one or more studies, you will be notified on-screen. At this point, you can review basic information about the studies and decide whether you wish to move forward to the next step in the process.

    4. Referral initiated only with your consent

    Should you choose to proceed, DecenTrialz will transmit your contact information — and only your contact information, to the research site associated with the selected trial(s). This referral allows the research team to follow up with you directly for:

    • A more comprehensive eligibility screening
    • Explanation of the study procedures and timelines
    • Informed consent discussion, as required by regulatory standards

    DecenTrialz will never disclose your complete health information, name, or location without your explicit consent.

    Important considerations

    • Pre-screening does not guarantee enrollment. Only the research team can determine your final eligibility after conducting their own assessments.
    • Participation is voluntary at every stage. You are free to decline a referral or discontinue at any time, with no obligation to proceed.
    • All decisions involve human oversight. DecenTrialz does not use automated systems to make enrollment decisions. All referrals and communications are reviewed under ethical and regulatory standards.

    Key Note: DecenTrialz acts solely as a pre-screening and referral facilitator. We do not conduct clinical trials and do not make final eligibility decisions. Our role is to streamline the discovery process for participants while maintaining high standards of privacy, safety, and compliance.

  • Terms You Should Know

    TermDescription
    Pre-screeningA basic check to see if you may qualify before official enrollment.
    IRBInstitutional Review Board, which reviews research to protect participant rights.
    Informed ConsentThe process of understanding a trial before voluntarily agreeing to join.
    De-identified DataData that has been stripped of personal identifiers.
    SponsorA company or organization funding the clinical trial.
    SiteA hospital, clinic, or research facility running the trial.
    CROContract Research Organization that supports sponsor needs.
    DashboardYour personalized control panel showing progress and activity.
  • Understanding Your Dashboard

    Your dashboard provides a real-time view of your activity on the platform.

    • Participants: View matched trials, application status, messages, and educational tips.
    • Sites: Track leads, pre-screen status, call logs, and scheduling.
    • Sponsors/CROs: Access heat maps, funnel analytics, and participant journey metrics across studies.

    All dashboards are mobile-friendly, secure, and updated in real time.

  • Using the Trial Search

    Participants can use the search tool to find clinical trials by:

    • Condition (e.g., Asthma, PCOS)
    • Zip code or city
    • Trial phase (optional)
    • Age or gender eligibility

    Each result shows a short trial summary, eligibility requirements, and whether you match. You can express interest directly from the result page.

  • Creating an Account

    Your onboarding experience on DecenTrialz begins with creating an account tailored to your role. Each user type has a customized journey.

    For Participants

    If you are joining DecenTrialz as a participant, here’s how to get started:

    Step-by-Step Registration Flow

    Step 1: Personal Information

    • Choose who you’re signing up for:
      • For Myself (must be 18 years or older)
      • On Behalf of Someone Else (e.g., for a child, parent, or dependent)
    • Fill in your:
      • First and last name
      • Email address
      • Date of birth
      • Gender (Male, Female, Transgender, Non-Binary)

    Key Note: You must be 18 years or older to sign up for yourself. If you are registering for a minor, you must proceed as a guardian under “On Behalf of Someone Else.”

    Step 2: Location Information

    • Enter your:
      • Zip or pin code
      • Full address

    This helps us match you with trials near your location.

    Step 3: Health Status and Trial Intent

    • Choose your health status:
      • I’m healthy and ready to volunteer
      • I’m seeking a trial for my condition
    • Add any medical conditions (e.g., Diabetes Type 2, Brain Cancer) if relevant.

    Key Note: You can skip condition selection if you are joining as a healthy volunteer. Entering your condition helps improve trial matching for treatment-based studies.

    Step 4: Verification and Consent

    • Complete the CAPTCHA verification.
    • Check the consent box to allow DecenTrialz to:
      • Use your submitted data to match you with suitable trials
      • Support you during onboarding, in accordance with our Privacy Policy
    • Click “Become a Volunteer” to complete the registration.

    Key Note: DecenTrialz only supports pre-screening and matching. Your final enrollment and consent will be handled by the research site managing the study.

  • Compliance with Privacy Regulations

    DecenTrialz operates in adherence to the following established compliance standards and regulations:

    • HIPAA (Health Insurance Portability and Accountability Act)
    • ISO 27001 Certified

    Our Commitments

    • Clear disclosures and consent workflows
    • Data minimization and purpose limitation
    • Right to access, correct, or delete your personal data
    • Transparent communication in case of any data breach

    Key Note: All platform features and workflows are reviewed by internal and external legal advisors to ensure compliance with U.S. and international research ethics.

  • Data De-identification and Aggregation

    To safeguard privacy, DecenTrialz uses standardized methods to de-identify participant information before it is used in analytics, reporting, or shared with sponsors and CROs.

    How Data Is Protected

    • Removal of direct identifiers (name, phone, address, etc.)
    • Aggregation across demographics and geographies
    • Use of secure pseudonymization techniques for longitudinal tracking

    When De-identified Data Is Used

    • For performance benchmarking across sites
    • To identify underserved communities
    • In reporting recruitment trends or dropout rates

    Key Note: De-identification procedures follow HIPAA Privacy Rule standards and are reviewed regularly for compliance with global data ethics norms.

  • Who has Access to Participant Data

    Access to participant data is strictly controlled and tiered based on role, function, and regulatory requirements.

    Access Levels

    • Participants can view and manage their own health profile, trial participation, and data-sharing settings.
    • Research Sites can access de-identified or limited data needed for pre-screening. Full access requires participant consent.
    • Sponsors and CROs only receive anonymized or aggregated data unless an IRB-approved agreement permits access to identifiable information.

    Access Protocols

    • All users must be authenticated before accessing any dashboard
    • Role-based permissions ensure data minimization
    • Audit trails log all access and data interactions

    Key Note: DecenTrialz does not sell participant data or share it with third parties for advertising or marketing purposes.

  • How Participant Data is Collected

    When users engage with DecenTrialz, we collect only the information necessary to support matching, study enrollment, and communication.

    Types of Data Collected

    • Personal details: name, age, gender, contact information
    • Health-related inputs: condition, symptoms, medical history
    • Study-specific inputs: location preferences, availability, trial status
    • System interactions: survey responses, task completion, engagement history

    Data Collection Methods

    • Direct input by participants through forms and dashboards
    • Data collection includes pre-screening health questionnaires to confirm eligibility
    • Passive system data (e.g., platform usage for reminders and alerts)

    Key Note: No sensitive health data is collected without explicit participant consent. Consent is obtained through transparent disclosures and IRB-approved consent forms.