User's blog

Category: Participant Journey

  • Eligibility Basics

    Before enrolling in any clinical trial, all participants must meet specific eligibility criteria. These criteria are set by the study’s sponsor and reviewed by ethics committees to ensure participant safety and scientific accuracy.

    At DecenTrialz, we introduce you to these eligibility principles during the pre-screening stage so that you can make informed decisions and avoid being matched with studies that are not appropriate for your individual profile.

    What does “Eligibility” mean in a clinical trial?

    In the context of clinical research, eligibility refers to the defined rules that determine who can or cannot participate in a particular study. These rules are based on:

    • The objectives and scientific goals of the study
    • The treatment or intervention being tested
    • Safety considerations specific to the trial
    • Characteristics required for valid data collection

    Eligibility criteria are developed by the trial sponsor—such as a pharmaceutical or biotechnology company—and reviewed by Institutional Review Boards (IRBs) and regulatory agencies.

    While formal eligibility is determined by the research site during screening, DecenTrialz uses a general version of these criteria in its pre-screener to help guide trial matching.

    Two Types of Criteria: Inclusion and Exclusion

    Eligibility is made up of two types of conditions that work together to define who can participate:

    Inclusion criteria

    These are the requirements you must meet in order to qualify for a study. Examples include:

    • Being within a specific age range
    • Having a diagnosis of the condition being studied
    • Meeting certain health markers or lab values

    Exclusion criteria

    These are conditions or factors that would prevent you from joining a particular study, usually to protect your safety or ensure accurate results. Examples include:

    • Having a co-existing medical condition that could interfere with the trial
    • Being pregnant or breastfeeding
    • Taking medications that may interact with the investigational treatment

    See below [Inclusion & Exclusion Criteria] for more detailed examples and guidance.

    Why eligibility criteria matter

    These criteria are not intended to exclude individuals unfairly. Rather, they serve several essential purposes:

    • Participant Safety: Minimizing health risks for volunteers
    • Scientific Validity: Ensuring data collected reflects the research question
    • Ethical Oversight: Guaranteeing fair treatment and regulatory compliance under IRB supervision

    Even if you appear to meet most of the criteria, only the research site has the authority to confirm eligibility following a full review of your health history and study requirements.

    How DecenTrialz supports the eligibility process

    • We use simplified eligibility logic in the pre-screener to help suggest trials that may align with your profile
    • You are never denied access to the platform if no match is found—you may update your responses at any time
    • If you are uncertain about your eligibility, we encourage you to speak directly with a study team, as outlined in [Can I Speak to Someone Before Joining?]

    Key Note: Eligibility is not a personal evaluation of your health, value, or importance. It is a safety-focused, scientifically determined process that ensures ethical and reliable clinical research. DecenTrialz helps you explore appropriate studies, but the final eligibility decision always rests with the clinical research team.

    Inclusion & exclusion criteria

    Every clinical trial is governed by a specific set of inclusion and exclusion criteria. These criteria determine who may be eligible to participate in a study and are critical for ensuring the safety of participants and the scientific reliability of the research.

    Understanding these criteria can help you decide whether to move forward with a clinical trial opportunity.

    What are inclusion criteria?

    Inclusion criteria are the specific traits or conditions a person must meet to be considered for participation in a clinical trial. These criteria are selected to support the study’s scientific objectives and ensure participant safety.

    Examples of common inclusion criteria:

    • Being within a certain age range (e.g., 18 to 65 years)
    • Having a confirmed diagnosis of the condition under study (e.g., Type 2 diabetes, asthma, depression)
    • Meeting specific lab test results or symptom severity thresholds
    • Willingness to comply with study procedures (e.g., attending clinic visits, using a mobile app, or wearing a monitoring device)
    • Residing within a specific geographic radius from the trial site

    Important: Meeting inclusion criteria does not guarantee that you will be accepted into the study. It means you may be considered for further screening.

    What are exclusion criteria?

    Exclusion criteria are the conditions, factors, or circumstances that disqualify someone from participating in a given study. These criteria are often established to minimize risks, prevent interference with study outcomes, or ensure participant well-being.

    Examples of common exclusion criteria:

    • Being pregnant or currently breastfeeding
    • Having another serious medical condition (e.g., advanced kidney disease, active cancer)
    • Taking medications that could interact with the investigational product
    • Recent participation in another clinical trial (e.g., within the last 30 days)
    • History of substance misuse or recent psychiatric hospitalization (depending on the study protocol)

    These criteria are not personal judgments — they are protective measures designed in accordance with ethical research practices.

    Why these criteria exist

    Eligibility criteria are developed through careful planning by the study sponsor and reviewed by Institutional Review Boards (IRBs), ethics committees, and regulatory agencies such as the U.S. Food and Drug Administration (FDA). They are designed to:

    • Safeguard participant health and minimize risk
    • Ensure the investigational treatment is tested in a scientifically valid way
    • Maintain consistency in study results by reducing confounding variables
    • Comply with ethical and regulatory frameworks

    How DecenTrialz applies these criteria

    During the pre-screening process, DecenTrialz:

    • Uses simplified versions of the inclusion and exclusion criteria to suggest trials that may be appropriate for your profile
    • Does not make final eligibility decisions — this is always handled by the clinical research site after a detailed medical review
    • Encourages you to ask questions and seek clarification if you are unsure about any eligibility factor

    Key Note: Meeting inclusion criteria and avoiding exclusion criteria does not guarantee enrollment in a trial. The final determination is made solely by the clinical research team based on a comprehensive review of your medical information. DecenTrialz provides early guidance to support your exploration but does not approve or deny participation.

    Healthy volunteer eligibility

    Not all clinical trials are limited to individuals with a diagnosed medical condition. Many studies are specifically designed for healthy volunteers, individuals who do not have the condition being studied but are willing to participate in research that supports scientific advancement and public health.

    This section outlines who qualifies as a healthy volunteer, the types of studies that may involve them, and how eligibility is determined.

    Who Is considered a healthy volunteer?

    A healthy volunteer is typically someone who:

    • Has no chronic illness or relevant medical diagnosis
    • Is not currently undergoing treatment for a serious condition
    • Reports being in overall good physical and mental health
    • Meets general eligibility criteria such as age, weight, lifestyle habits, and other non-medical factors

    Some studies may still include additional requirements, such as:

    • Body Mass Index (BMI) within a specific range
    • No history of certain surgeries or substance use
    • No recent participation in other clinical trials (e.g., within the last 30–90 days)

    Eligibility is always defined by the research protocol and may vary from one study to another.

    What do healthy volunteers contribute to?

    Healthy volunteers are essential in a wide range of clinical research, particularly in:

    • Phase 1 trials, which test new medications for safety, dosage, and side effects
    • Preventive or wellness studies, such as vaccine trials or lifestyle interventions
    • Behavioral and observational research, including studies involving digital tools, nutrition tracking, or wearable devices

    By participating, healthy volunteers help researchers:

    • Understand how investigational products interact with the human body
    • Compare results between individuals with and without the condition being studied
    • Generate baseline data that supports future medical breakthroughs

    How matching works for healthy volunteers on DecenTrialz

    If you indicate in the pre-screener that you are in good general health:

    • The platform filters for trials actively seeking healthy volunteers
    • You will not be shown condition-specific trials unless they allow participation from healthy individuals (e.g., as part of a control group)
    • You may be matched with studies related to prevention, early diagnostics, general health, or lifestyle research

    Even if you do not have a medical condition, you must still meet the study’s eligibility requirements. Final eligibility is confirmed by the research site after a formal screening process.

    Is it safe to participate as a healthy volunteer?

    Yes. All clinical trials — including those involving healthy volunteers — are subject to:

    • Ethical oversight by Institutional Review Boards (IRBs)
    • Compliance with national and international research regulations
    • Mandatory informed consent processes

    Before participating, you will receive:

    • A clear explanation of potential risks, study procedures, and your rights
    • Opportunities to ask questions at any time
    • The ability to withdraw from the study for any reason, without penalty

    Key Note: Healthy volunteers play a vital role in the advancement of medical science. Whether contributing to the development of safer treatments, preventive strategies, or digital health tools, your involvement supports future care innovations. DecenTrialz will only match you with studies suitable for individuals without a diagnosed condition, and participation is always voluntary.

  • Can I talk to my doctor about this?

    Yes. Participants are encouraged to consult with their healthcare provider before making any decision regarding clinical trial participation.

    Choosing whether to join a clinical trial is a personal and often complex decision. Involving your primary care physician, specialist, or another trusted healthcare professional can help you evaluate whether a study is appropriate for your medical needs, preferences, and ongoing care.

    This section explains the benefits of speaking with your doctor and how to prepare for the conversation.

    Why it may be beneficial to consult your doctor

    Your healthcare provider can offer valuable insights based on your personal medical history and ongoing treatment. Specifically, your doctor:

    • Understands your complete medical background and existing diagnoses
    • Can help assess whether participation is medically advisable
    • May have knowledge of potential medication interactions or safety concerns
    • Can assist in interpreting the trial’s potential risks and benefits in context
    • May be familiar with clinical research and help clarify consent forms or scientific terminology

    When you may choose to speak with your doctor

    You may consult with your physician at any point in the process, including:

    • Before completing the pre-screener, to evaluate whether trial participation is appropriate for your condition
    • After being matched, but prior to consenting to referral
    • After referral, while reviewing informed consent forms or other study materials
    • At any stage, there is no time pressure, and participation decisions should be made thoughtfully

    While there is no requirement to involve your doctor, doing so can increase your confidence and support your decision-making process.

    What to Bring to the Conversation

    To make your discussion with your physician more productive, consider bringing:

    • A copy or summary of the trial description from the DecenTrialz platform
    • A list of your questions or concerns about the study
    • Any emails or documents you may have received from the research site (if referred)

    You may wish to explain that you are exploring participation and would value their medical opinion regarding how the trial might affect your health, routine care, or medications.

    Will my doctor be contacted automatically?

    No. Neither DecenTrialz nor the research site will contact your physician unless:

    • You explicitly request or authorize that they be involved
    • You list your physician as a collaborator in your care
    • The study protocol requires coordination with your existing care team, which may apply in complex cases

    Your involvement of your doctor is entirely optional and always under your control.

    Key Note: Consulting with your healthcare provider can help you make a fully informed and supported decision. Clinical trial participation is entirely voluntary. You deserve to have all available information, including your physician’s guidance, when considering your options. Asking questions or seeking a second opinion is not only appropriate, it is encouraged.

  • Who will contact me?

    Once you complete the pre-screener and explicitly consent to be referred to a clinical trial, your contact information is securely shared with the clinical research site responsible for conducting the study. At that point, DecenTrialz steps out of the process, and communication is managed directly by the site.

    This section outlines who may contact you, how they will identify themselves, and what you can expect during the initial communication phase.

    Who typically reaches out?

    The first individual to contact you is usually a staff member from the research site. Depending on the site’s organizational structure, this may include:

    • Clinical Research Coordinator (CRC):
      Responsible for coordinating communications, scheduling, and managing participant logistics.
    • Study Nurse or Research Assistant:
      Often supports eligibility screening, participant education, and study-related procedures.
    • Patient Recruitment Specialist:
      May assist with guiding new participants through the onboarding and consent process.
    • Principal Investigator or Sub-Investigator (Less Common Initially):
      Licensed physicians overseeing the trial; they may connect with you at a later stage during consent discussions or medical evaluations.

    Please note: You will not be contacted by DecenTrialz after referral unless you request support from our platform team

    What will they say when they contact you?

    The research site staff will generally:

    • Identify themselves and state the name of the study
    • Confirm that you expressed interest through the DecenTrialz platform
    • Ask a few brief follow-up questions related to your eligibility
    • Offer to provide additional study information or schedule a formal screening appointment
    • Share key documents such as the participant information sheet, informed consent form, or study timeline

    You are welcome to ask any questions you may have at this time.

    How will they contact you?

    They will use the contact method you selected during the pre-screener process, which may include:

    • Phone call
    • Email
    • Text message (if explicitly permitted by you during pre-screening)

    You are not obligated to respond. If you are no longer interested, you may decline the contact, delay your response, or inform the site of your decision not to proceed.

    What if I do not hear back immediately?

    Response times vary between research sites. In general:

    • Most sites respond within 24 to 72 hours
    • Some sites may take longer depending on staff capacity, recruitment timelines, or study phase

    If more than one week has passed and you have not received a response:

    • You may follow up directly with the research site (if contact information was provided)
    • Alternatively, you may contact support@decentrialz.com for assistance

    While DecenTrialz can help facilitate a follow-up request, final response times are determined solely by the research site.

    Key Note: Once you opt in, all next steps are coordinated by the clinical research site. Any individual who contacts you will be a qualified member of the study team, trained to assist you throughout the screening and enrollment process. You are never required to continue if you are uncertain, and you may request additional information before making a decision.

  • What if I’m not interested after matching?

    Being matched to a clinical trial through DecenTrialz does not obligate you to participate. We understand that even when a study appears to align with your profile, you may decide not to move forward, and that decision is entirely yours.

    This section outlines your options if you are not interested in a study after matching and explains how DecenTrialz respects and handles that choice.

    You Remain in Control at Every Stage

    When you are matched to a trial on the DecenTrialz platform:

    • You will be presented with study details and basic eligibility information
    • You must manually opt in before any of your information is shared with a research site
    • If you choose not to proceed, no referral occurs and no data is shared

    There is no obligation to respond and no requirement to explain your decision. Simply choosing not to click the “Refer Me” or “Proceed” button ensures your data remains private.

    If You Have Already Clicked “Refer” but Changed Your Mind

    If you initially opted in but later decide not to continue, you still have full control. You may:

    • Decline when contacted by the research site
    • Notify the site directly that you are no longer interested
    • Email our support team at support@decentrialz.com, and we can assist in informing the site on your behalf

    You are allowed to change your mind at any point — even after referral, even after being contacted, and even during the research site’s screening process. You are never obligated to proceed further than you feel comfortable.

    Will This Affect Future Trial Matching?

    No. Choosing not to proceed with one study does not affect your future use of the DecenTrialz platform. Specifically:

    • You will continue to have access to other trial opportunities
    • You remain eligible for other studies unless a specific study protocol requires a waiting period (e.g., no trial participation within the past 30 days)
    • You can update your responses, health status, or participation preferences at any time by logging into your profile

    Common and Valid Reasons for Opting Out

    Participants choose not to proceed for many reasons, including:

    • The study location is not convenient
    • The required procedures or time commitment are not feasible
    • They prefer to consult with their physician before continuing
    • They are not ready to participate at this time

    All reasons are valid. You are never expected to justify your decision.

    Key Note: Participation in clinical research is always voluntary. DecenTrialz is committed to a no-pressure, ethics-first approach to trial matching. Declining to participate in a current opportunity does not prevent you from exploring future studies. You are welcome to return at any time to explore options that better align with your needs and preferences.

  • Site or sponsor contact process

    After completing the pre-screener and providing consent to be referred, DecenTrialz securely transmits your information to the clinical research team associated with the matched study. This section outlines how that contact process works, who may reach out to you, and what to expect during this early phase of communication.

    Who will contact you and why?

    Following referral, the research site — which may be a hospital, clinic, academic medical center, or independent research facility — becomes responsible for initiating direct communication. While some sites may be affiliated with a study sponsor (e.g., a pharmaceutical or biotechnology company), you will only be contacted by the site staff or their designated personnel.

    You may be contacted by:

    • A Clinical Research Coordinator (CRC)
    • A Research Nurse
    • A Participant Recruitment or Engagement Specialist

    Their role is to begin the official screening process, confirm your interest, provide study details, and respond to your questions.

    How will they contact you?

    The research site team will use the preferred contact method you selected during pre-screening. This may include:

    • Phone call
    • Email communication
    • Text message, if you explicitly consented to that method

    In their initial outreach, they may reference:

    • The study title
    • The name of the research site or principal investigator
    • That you expressed interest via the DecenTrialz platform

    Note: You will not be contacted unless you have explicitly consented to referral.

    What Information will the research site receive?

    The information shared with the research site is limited to:

    • Your name and contact details
    • Your pre-screener responses
    • Any communication preferences you provided (e.g., best times to reach you)

    The research site will not receive:

    • Your complete medical history or records
    • Insurance or billing information
    • Any unrelated personal data

    What to expect during initial contact

    During their first communication with you, the research site team may:

    • Confirm that you remain interested in the study
    • Ask follow-up questions to assess your eligibility
    • Provide an overview of the study purpose, procedures, and timelines
    • Offer to schedule a screening appointment or virtual consultation
    • Share additional materials, such as the informed consent form or reimbursement policy

    This is also your opportunity to ask questions about the trial, your rights as a participant, and what the study involves.

    Key Note: Once you are referred, DecenTrialz no longer participates in the communication process. All further discussions occur directly between you and the research site. You are under no obligation to respond or move forward. You may withdraw your interest at any time, and the research site is ethically required to respect your privacy and decision without pressure.

  • Informed consent explained

    Informed consent is a foundational component of ethical clinical research. While formal informed consent is required before a participant can officially join a clinical trial, DecenTrialz ensures that you are also provided with clear, understandable information prior to the referral stage, during pre-screening.

    This section explains how the principles of informed consent apply specifically to the DecenTrialz platform and what you can expect before any of your information is shared with a research team.

    What Is informed consent in clinical research?

    Informed consent is not a one-time form, it is an ongoing, transparent process through which you:

    • Receive relevant and understandable information about the study
    • Are given the opportunity to ask questions and evaluate the information
    • Voluntarily agree (or decline) to participate, without pressure or coercion

    In the context of full trial enrollment, informed consent typically involves a detailed written consent form, a discussion with clinical staff, and your documented agreement.

    At the pre-screening stage, this process is more limited but still critically important to ensure your autonomy and privacy.

    How Informed Consent Works at the Pre-Screening Stage

    Before any personal information is shared with a clinical research site, DecenTrialz presents you with a clear consent notice. This notice:

    • Describes exactly what data will be shared, such as your contact details and pre-screener responses
    • Identifies the intended recipient — a specific research site conducting the matched trial
    • Explains the purpose of the data sharing — to initiate contact for further eligibility screening
    • Clarifies that referral is entirely optional and occurs only if you provide explicit confirmation

    You will be required to actively opt in to the referral. If you choose not to proceed, no data will be transmitted. There are no penalties or consequences for declining.

    What this consent does not include

    The consent process at the pre-screening stage:

    • Does not enroll you in any clinical trial
    • Does not authorize any medical procedures, assessments, or study-related tests
    • Does not replace the formal informed consent process that will occur at the research site if you move forward

    Should you proceed with a referral, the clinical research site will conduct its own detailed informed consent process, in compliance with IRB, HIPAA, and FDA requirements, before any study activities begin.

    Why consent still matters at the pre-screening stage

    Although you are not formally joining a study at this point, the handling of your health-related and contact information still requires strong ethical safeguards. DecenTrialz ensures that:

    • You are clearly informed about what will happen with your information
    • You maintain full control over whether your data is shared
    • You may withdraw or decline at any time without impact on future opportunities

    Participation in pre-screening is fully voluntary, and your rights are respected throughout the process.

    Key Note: DecenTrialz adheres to established research ethics and regulatory standards, including HIPAA, IRB oversight, and clinical consent principles. You will never be referred to a clinical research site without your explicit, informed consent, and no personal data will be shared without your direct approval.

    Disclaimer: DecenTrialz does not conduct clinical trials. The platform only facilitates pre-screening to help identify potential participant eligibility. All study activities, medical evaluations, and final enrollment decisions are carried out exclusively by the independent research sites or sponsors responsible for each clinical trial.

  • What happens after matching

    Once you have been matched to a clinical trial on the DecenTrialz platform, you may choose whether to proceed with expressing interest in participation. If you opt in, DecenTrialz initiates a secure, consent-based referral to the clinical research site responsible for conducting the study.

    This section outlines the steps that follow a trial match and what you can expect throughout the referral process.

    Step-by-Step: What Happens After a Trial Match

    1. Review of trial details

    After a potential match is identified, the platform will present you with an overview of the clinical trial, including:

    • A brief summary of the study’s objectives
    • The medical condition or research focus
    • Location of the study site or indication of remote participation
    • Key eligibility criteria
    • Type of intervention or participation involved

    You are encouraged to review this information carefully before making a decision.

    2. Voluntary referral opt-in

    If you are interested in proceeding, you may choose to be referred to the research site. Referral is entirely voluntary and will not occur without your explicit consent.

    At this stage, you may be asked to:

    • Confirm your contact information
    • Acknowledge a consent notification or confirmation message regarding the referral

    3. Secure referral to the research site

    Upon opt-in, DecenTrialz will securely transmit your basic pre-screener responses and contact details to the research team associated with the selected trial. This allows the site to:

    • Follow up with you to conduct further eligibility screening
    • Request additional information relevant to the study
    • Schedule a consultation or screening appointment

    Contact may occur via phone or email, based on the preferences you previously indicated.

    4. Research site screening process

    Once referred, the clinical research site will conduct its own evaluation to determine final eligibility. This may include:

    • Detailed review of your medical history and current health status
    • Laboratory tests, diagnostic procedures, or questionnaires (as required by the protocol)
    • Explanation of informed consent, including study risks, procedures, and your rights as a participant

    This process is conducted entirely by the research site and is independent of DecenTrialz.

    Important clarifications

    • DecenTrialz is not a clinical trial site. We do not conduct research studies or determine final eligibility.
    • You are never obligated to continue. You may decline participation at any time before or after the referral.
    • Support is available. You may contact both the DecenTrialz support team and the research site staff with any questions during this stage.

    Key Note: Being matched and referred to a study does not guarantee enrollment or eligibility. The final determination is made solely by the clinical research team after completing their own review. DecenTrialz acts only as a facilitator, enabling a secure and participant-controlled connection between you and the trial site.

  • What types of trials might I be matched to?

    The types of clinical trials you may be matched to on the DecenTrialz platform are based entirely on the information you provide during the pre-screening process. This includes your general health status, current or past medical conditions, symptoms (if any), geographic location, and preferences regarding travel or remote participation.

    This section provides an overview of the primary trial categories you may be matched with and what to expect if a match occurs.

    How matches are determined

    DecenTrialz uses your responses to the pre-screener to evaluate alignment with general eligibility parameters submitted by trial sponsors or research sites. If your information corresponds to these parameters, you may be matched to:

    • One or more actively recruiting clinical trials
    • Trials located in your region or offering remote participation options
    • Studies seeking individuals with specific conditions, risk factors, or healthy volunteer profiles

    Please note: A match does not indicate formal qualification or enrollment. It is a preliminary indication of possible eligibility. All matched trials require additional screening by the research site team before enrollment can occur.

    Common trial types you may be matched

    1. Condition-Specific Trials

    These trials recruit participants who have a confirmed diagnosis of a particular medical condition. Examples include:

    • Type 2 Diabetes
    • Asthma or COPD
    • Depression or Anxiety Disorders
    • Migraine or Chronic Headache
    • Autoimmune Conditions (e.g., Lupus, Rheumatoid Arthritis)

    During pre-screening, you may be asked about your diagnosis, current treatment regimen, and symptom severity to determine alignment with the trial’s criteria.

    2. Preventive or Wellness Trials

    These studies often focus on individuals who are at risk of developing a condition or are interested in preventive care strategies. Common examples include:

    • Vaccine development trials
    • Lifestyle intervention studies (e.g., diet, exercise, or stress management)
    • Genetic screening or early detection research

    These trials may or may not require a current diagnosis and are often open to broader participant groups.

    3. Healthy Volunteer Trials

    If you report being in good general health with no major diagnoses, you may be eligible for trials specifically designed for healthy individuals. These trials typically involve:

    • Phase 1 drug or device safety studies
    • Observational studies for baseline physiological or behavioral data
    • Research on sleep, nutrition, exercise, or digital health tools

    For more details, see [Healthy Volunteer Eligibility].

    4. Remote or Decentralized Trials

    Depending on your geographic location and available studies, you may be matched to trials that offer:

    • Fully virtual participation via mobile applications or telehealth
    • Hybrid designs combining in-person and remote procedures
    • Home-based study kits, wearable devices, or remote monitoring tools

    These models are particularly beneficial for individuals with limited access to clinical trial sites or who prefer minimal travel.

    What you will see If a match occurs

    If your responses result in one or more potential matches, the platform will display:

    • The title of each trial and a brief description of the study’s focus
    • The location of the research site or confirmation of remote participation
    • A summary of basic eligibility criteria
    • A clear option to learn more or request a referral to the research site

    You are never automatically enrolled in a trial. All participation decisions are made voluntarily and require your informed consent before any further steps are taken.

    Key Note: The types of trials you may be matched with depend on your submitted responses, your location, and the availability of studies at the time of pre-screening. If no match is currently available, you may return at a later time or update your profile. New trials are added regularly to the DecenTrialz platform.

  • Can I speak to someone before joining?

    Yes. Participants are encouraged to speak with a support representative prior to proceeding with any referral or next steps.

    At DecenTrialz, we recognize that choosing to participate in a clinical trial is a personal and significant decision. Individuals may wish to seek clarification before continuing, particularly if they have questions regarding eligibility, trial details, data privacy, or next steps in the process.

    This section outlines who you may speak with, what type of support is available, and how to request assistance at any stage of the pre-screening or trial-matching process.

    When it may be helpful to speak with someone

    You may consider contacting support if:

    • You have questions about a specific trial or matching results
    • You are uncertain whether your medical history may impact eligibility
    • You would like additional information about how referrals work
    • You are seeking clarification on data privacy or information handling
    • You would prefer reassurance or further explanation before continuing

    These are common and appropriate reasons to seek assistance. DecenTrialz provides accessible support options to ensure you are fully informed prior to making any decisions.

    Available support options

    DecenTrialz offers two levels of participant support:

    1. DecenTrialz Platform Support Team

    The platform support team can assist with:

    • Clarifying how the DecenTrialz matching and referral system operates
    • Providing guidance on navigating the platform and understanding next steps
    • Explaining how your data is collected, stored, and protected under HIPAA standards

    Please note: The DecenTrialz support team is not authorized to provide clinical advice or determine trial-specific eligibility.

    Contact information:

    Email: support@decentrialz.com

    2. Research Site Personnel (Post-Referral Only)

    Once you opt in to be referred to a clinical trial:

    • A representative from the research site may contact you
    • They are qualified to answer study-specific clinical questions, explain procedures, and discuss potential risks and benefits
    • This communication occurs only after you have provided explicit consent to be referred

    How to request support

    You may request assistance at any point—before, during, or after completing the pre-screener—using any of the following methods:

    • Clicking the “Need Help?” or “Contact Support” link within the DecenTrialz platform
    • Sending an email to support@decentrialz.com

    A member of the support team will respond as promptly as possible to provide assistance or direct you to the appropriate contact.

    Key Note: There is no obligation to proceed with a referral or enroll in a clinical trial simply because you have been matched. DecenTrialz encourages all prospective participants to seek clarification and ask questions before making any decisions. Participation in research should always be informed, voluntary, and supported by transparent communication.

  • Completing the pre-screener

    The pre-screener is the initial step in identifying whether you may qualify for one or more clinical trials listed on the DecenTrialz platform. It is a brief, confidential questionnaire designed to assess general eligibility before any information is shared with research teams.

    This section explains the purpose of the pre-screener, what types of questions you will encounter, and how your information is securely handled.

    Purpose of the pre-screener

    The primary objective of the pre-screener is to gather essential, non-sensitive details about your health background and location. This enables our platform to:

    • Identify clinical trials that align with your general eligibility profile
    • Minimize unnecessary outreach from trials for which you clearly do not qualify
    • Ensure your control over when and how your data is shared with research teams

    Please note: Completing the pre-screener does not enroll you in a clinical trial. It is an optional, informational step intended to help you explore available research opportunities.

    What to expect during the pre-screener

    The pre-screener is divided into two core categories of questions:

    a. Basic health and medical information

    These questions help us determine if you may be a suitable match for clinical trials with specific health-related criteria. You may be asked about:

    • Any current or past medical diagnoses
    • Ongoing medications or therapies
    • Relevant surgical history or major health events
    • Your age and biological sex (required for eligibility in many trials)

    You will not be asked for sensitive data such as your Social Security Number, insurance details, or complete medical records.

    For more information, see below [Health Questions].

    b. Location and contact details

    To ensure you are matched with trials based on geographic feasibility, we will ask for:

    • Your city and state of residence
    • Willingness or ability to travel, if needed
    • Your preferred contact method (e.g., phone number or email address)

    This allows our platform to prioritize studies in your region or those that offer remote participation.

    For more information, see below [Location/Contact Details].

    Estimated completion Time

    The pre-screener typically takes less than five minutes to complete. You may pause the process and return later, provided your browser session remains open.

    Data security and privacy

    Your responses are handled in accordance with the highest data protection standards, including compliance with the Health Insurance Portability and Accountability Act (HIPAA). Specifically:

    • Your information is never shared with any research team without your explicit consent
    • All data is encrypted and stored using secure, access-controlled systems
    • The information you provide is used solely for clinical trial matching and referral — never for commercial advertising or third-party marketing

    Key Note: You are not obligated to complete the pre-screener or proceed beyond any step. You may exit the process at any time. The purpose of the pre-screener is to provide you with a secure, transparent way to explore trial options at your own pace and with full control over your participation decisions.

    Health questions

    As part of the pre-screener process on the DecenTrialz platform, you will be asked a short series of general health questions. These questions are designed to determine whether your current medical profile may preliminarily align with the eligibility criteria of clinical trials listed on our platform.

    This is not a diagnostic evaluation or full medical assessment. Rather, it serves as an early, participant-controlled screening tool to help match you with relevant research opportunities.

    Why these questions are asked

    Each clinical trial is governed by specific inclusion and exclusion criteria that define who may participate. These criteria are determined by the study sponsor or research investigators and often include considerations such as:

    • The medical condition under investigation (e.g., Type 2 Diabetes, Asthma, Anxiety)
    • The severity or stage of the condition
    • Prior diagnoses, treatments, or procedures
    • Current medications, symptoms, or health risks

    The health-related questions in the pre-screener allow the platform to filter out trials that would clearly not be appropriate for your profile. This protects your time, privacy, and avoids unnecessary outreach from research sites.

    Examples of health questions you may encounter

    The following are common categories of questions that may appear in the pre-screener:

    1. Diagnosis or Condition Status

    These questions help assess whether you have previously or currently experience the condition being studied.

    • Have you ever been diagnosed with [specific condition]?
    • Are you currently receiving treatment for this condition?

    2. Treatment History

    These questions identify whether you have undergone relevant medical procedures or used specific medications.

    • Have you taken medication for this condition within the past six months?
    • Have you had any surgeries related to this diagnosis?

    3. Current Symptoms

    These questions gather insight into present-day health experiences that may be relevant to study eligibility.

    • Are you experiencing any of the following symptoms?
    • How often do you experience [specific symptom]?

    4. Other Relevant Medical Factors

    Certain clinical trials require awareness of additional health conditions or physiological states.

    • Are you currently pregnant or breastfeeding?
    • Do you use any implanted medical devices (e.g., pacemaker, insulin pump)?

    Important: You are not required to upload test reports, disclose insurance details, or share physician records at this stage.

    How your responses are used

    • Your responses are automatically compared with the general eligibility filters of active clinical trials.
    • DecenTrialz does not make medical decisions or diagnoses based on your answers.
    • You may review and edit your responses before submitting them.
    • No personal or health-related information is shared with any third party unless you explicitly opt in for referral.

    Key Note: You may skip individual questions or exit the pre-screener entirely at any time. Your participation in the pre-screener is voluntary and confidential. The information you provide is used exclusively to guide your exploration of potential clinical trial opportunities and is never used for advertising or shared for commercial purposes.

    Location and contact details

    In addition to health-related questions, the DecenTrialz pre-screener includes a brief section where you are asked to provide your geographic location and preferred contact method. These details are essential for ensuring that any potential trial matches are geographically relevant or offer remote participation options.

    All information you provide is stored securely and will not be shared with any research team or third party without your explicit consent.

    Why location and contact information are important

    Most clinical trials are hosted at specific research sites, including hospitals, clinics, or academic research institutions. While some studies may offer remote or hybrid options, many still require in-person visits for procedures, labs, or assessments.

    Providing your general location allows DecenTrialz to:

    • Match you with studies near your place of residence or within your preferred travel range
    • Filter out studies that are not available in your region
    • Help identify decentralized or remote-participation trials, when applicable

    Information You May Be Asked to Provide

    The location and contact section of the pre-screener typically requests the following details:

    1. City, state, and country

    You will be asked to enter your current place of residence, which may include:

    • Your city or town
    • The applicable U.S. state (for domestic participants)
    • Your country of residence

    This helps narrow down geographically relevant trials based on eligibility and trial site proximity.

    2. Willingness to travel

    Some studies may ask participants to visit a trial site periodically. You may be asked:

    • Whether you are open to traveling for a clinical study
    • Your maximum preferred travel range (e.g., within 10 miles, 25 miles, or more)

    These questions are optional and do not impact your ability to view or be matched to remote-eligible studies.

    3. Preferred method of contact

    In the event that you are matched to a trial and choose to proceed with a referral, the research team may need a way to contact you. You may be asked for:

    • Your name (optional during pre-screening)
    • A phone number and/or email address
    • Your preferred method of communication (e.g., phone call, text, or email)

    You are free to indicate your contact preferences or opt out of providing this information if you do not wish to proceed further.

    Data privacy and consent

    • Your location and contact details are not shared with any trial site unless you opt in and provide explicit consent
    • If you choose to move forward with a referral, only the information necessary to initiate contact is securely transmitted to the research team
    • You may update or request the deletion of your information at any time by contacting support@decentrialz.com

    Key Note: Providing accurate location and contact information helps improve the precision of trial matching. However, sharing your contact information is entirely voluntary. You will never be contacted by a research site unless you have explicitly agreed to be referred, and you may withdraw or modify your information at any time.